Natty Gann (played by Meredith Salenger) is a twelve year old Depression era girl whose single-parent father leaves her behind in Chicago while he goes to Washington State to look for work in the timber industry. Natty runs away from the guardian she was left with to follow Dad. She befriends and is befriended by a wolf that has been abused in dog fights, hops a freight train west, and is presumed dead when her wallet is found after the train crashes. Dad gets bitter and endangers himself in his new job. Meanwhile Natty has a series of adventures and mis- adventures in various farmhouses, police stations, hobo camps, reform schools, and boxcars.

The carpenter, Jesus of Nazareth, tormented by the temptations of demons, the guilt of making crosses for the Romans, pity for men and the world, and the constant call of God, sets out to find what God wills for Him. But as His mission nears fulfillment, He must face the greatest temptation; the normal life of a good man. Based, not on the Gospels, but on Nikos Kazantzakis' novel of the same name.